Aetna Autologous Chondrocyte Implantation prior authorization requirements (2026)

What Aetna generally requires to approve Autologous Chondrocyte Implantation (CPT 27412, J7330, S2112), for Commercial plans. Yes. Aetna generally requires prior authorization for Autologous Chondrocyte Implantation (CPT 27412, J7330, S2112).

General reference compiled from public sources, last verified 2026-06-13. This is not a coverage determination or medical advice. Always confirm current requirements with Aetna before submitting.

Medical-necessity criteria Aetna generally applies

Aetna (CPB 0247) considers autologous chondrocyte implantation medically necessary for a symptomatic, disabling full-thickness focal articular cartilage defect on a load-bearing surface of the femoral condyle (medial, lateral, or trochlear), down to but not through subchondral bone, when ALL of the following are met: failure of conservative therapy (minimum 6 weeks of physical therapy within the past year); age 15 or older with documented growth-plate closure (adults under 55); BMI 35 or less; and an able, cooperative candidate for post-operative weight-bearing and activity restrictions and completion of rehabilitation.

Diagnoses that commonly support medical necessity

ICD-10-CM diagnoses frequently associated with medical necessity for Autologous Chondrocyte Implantation. Confirm the covered diagnosis list against the current Aetna policy.

M24.169Other articular cartilage disorders, unspecified knee

Commonly required documentation

  • All medical records requested must be submitted

How to submit

  • Method: portal
  • Typical turnaround: about 3 days

Source

Summarized (not verbatim) from Aetna Clinical Policy Bulletin 0247, Autologous Chondrocyte Implantation. Source: View the source policy. Last verified 2026-06-13.

Frequently asked questions

Does Aetna require prior authorization for Autologous Chondrocyte Implantation?

Yes. Aetna generally requires prior authorization for Autologous Chondrocyte Implantation (CPT 27412, J7330, S2112).

What does Aetna require to approve Autologous Chondrocyte Implantation?

Aetna (CPB 0247) considers autologous chondrocyte implantation medically necessary for a symptomatic, disabling full-thickness focal articular cartilage defect on a load-bearing surface of the femoral condyle (medial, lateral, or trochlear), down to but not through subchondral bone, when ALL of the following are met: failure of conservative therapy (minimum 6 weeks of physical therapy within the p… Always confirm against the current Aetna policy.

How long does a Aetna prior authorization take?

Aetna typically decides Autologous Chondrocyte Implantation requests in about 3 days. Timeframes vary; check the payer portal.

Submitting Autologous Chondrocyte Implantation to Aetna?

Praxigen checks your clinical note against these criteria before you submit and drafts a policy-cited appeal if it is denied. You review and submit; nothing is sent automatically.

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Other Aetna prior authorization requirements

ACL ReconstructionAnterior Cervical Discectomy and FusionArthroscopic Hip Surgery for Impingement Syndrome Including Labral RepairArtificial Intervertebral Disc Surgery (Cervical Spine)Artificial Intervertebral Disc Surgery (Lumbar Spine)Bunionectomy (Hallux Valgus Correction)Cervical, Lumbar and Thoracic Laminectomy and/or Laminotomy ProceduresChiari Malformation Decompression SurgeryCochlear Device and/or ImplantationCT Abdomen and Pelvis with contrastCTA Chest (e.g., pulmonary embolism)Custom Foot Orthotics

Related guides

Why was my prior authorization denied? Top reasons and how to fix eachHow to write a prior authorization appeal that cites policy